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Pharmacology

59. K. K. Coti, Y. Wang, C.-C. Chen, Z. T. F. Yu, M. Selke, W. Lu, W.-Y. Lin, C. K.-F. Shen, A. Yeh, H.-R. Tseng (2008) Dynamic Micro-/Nano-Reactor. Submitted.

58. W.-Y. Lin, Y.-C. Chen, K. Liu, Y. Wang, S. Olma, K. Faull, N. Satyamurthy, M. E. Phelps, R. M. van Dam, C. K.-F. Shen, H.-R. Tseng (2008) Radiochemical Syntheses of 3′-Deoxy-3′-[18F]Fluoro-L-Thymidine and 2-(1-{6-[(2 [18F]Fluoroethyl)Methylamino]-2-Naphthyl} Ethylidene) Malononitrile Using an Integrated Microfluidic Device. Submitted.

57. Z. T. F. Yu, K. Kamei, C. J. Shu, R. Silverman, C. G. Radu, O. N. Witte, H.-R. Tseng (2008) An Integrated Microfluidic Chip for Parallel Culture and Multiparametric Analysis of Murine and Human Cell Lines. Submitted.

56. S. Hou, C. K.-F. Shen, Zeta T. F. Yu, S. Wang, X. Fang, H.-R. Tseng (2008) Hydrodynamically Focused Stream as a Dynamic Template for Electrochemical Growth of Single Conducting Polymer Nanowires. Angew. Chem. Int. Ed. 47: ASAP.

55. K. K. Coti, Y. Wang, J. Wang, M. M. Alam, J.-J. Shyue, A. Yeh, W. Lu, N. P. Padture, H.-R. Tseng(2007) Individually Addressable Crystalline Conducting polymer Nanowires in a Microelectrode Sensor Array. Nanotechnology 18: 424021 (7 pp).

54. G.Sui,C.-C. Lee, K. Kamei, H.-J. Li, J.-Y. Wang, J. Wang, H. R. Herschman, H.-R. Tseng (2007) A Microfluidic Platform for Sequential Ligand Labeling and Cell Binding Analysis. Biomedical Microdevices 9: 301-305

53. G. Sui, J. Wang, H.-R. Tseng (2006) Playing Reactions in Hand. Nano Today, 1: 6-7.

52. G. Sui, J. Wang, C.C. Lee, S. P. Lee, J. V. Leyton, A. M. Wu, H.-R. Tseng (2006) Solution-Phase Surface Modification in Intact Poly(dimethylsiloxane) Microfluidic Channels. Anal. Chem. 78: 5543-5551.

51. J. Wang, G. Sui, V. P. Mocharla, R. J. Lin, M. E. Phelps, H. C. Kolb, H.-R. Tseng (2006) Integrated Microfluidics for Parallel Screening of In Situ Click Chemistry Library. Angew. Chem. Int. Ed. 45: 5276-5281.

50. J. Wang, Y. L. Bunimovich, G. Sui, S. Savvas, Y. Guo, J. R. Heath, H.-R. Tseng (2006) Electrochemical Fabrication of Conducting Polymer Nanowires in an Integrated Microfluidic System. Chem. Commun. 3075-3077.

49. C.-C. Lee, G. Sui, A. Elizarov, C. J. Shu, Y.-S. Shin, A. N. Doole, D. Stout, O. N. Witte, H. C. Kolb, N. Satyamurthy, J. R. Heath, M. E. Phelps, S. R. Quake, H.-R. Tseng (2005) Multi-Step Synthesis of a Radiolabeled Imaging Probe in Integrated Microfluidics. Science 310: 1793-1796.

48. M. M. Alam, J. Wang, Y. Guo, S. P. Lee, H.-R. Tseng (2005) Electrolyte-Gated Transistors Based on Conducting Polymer Nanowire Junction Arrays. J. Phys. Chem. B 109: 12777-12784.

47. J. Wang, M. M. Alam, H.-R. Tseng (2005) Individually Addressable Conducting Polymer Nanowire Electrode Junctions That Function as Gas Sensors. Mater. Res. Soc. Symp. Proc.  828: A2.10.1. 

46. J. Wang, S. Chan, R. R. Carlson, Y. Luo, G. Ge, R. S. Ries, J. R. Heath, H.-R. Tseng (2004) Electrochemically Fabricated Polyaniline Nanoframework Electrode Junctions That Function as Resistive Sensors. Nano Lett. 4: 1693-1697. 

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Prior to Pharmacology

45. B. Brough, B. H. Northrop, J. J. Schmidt, H.-R. Tseng, K. N. Houk, J. F. Stoddart, C.-M. Ho (2006) Evaluation of Synthetic Linear Motor-molecule Actuation Energetics. Proc. Natl. Acad. Sci. USA. 103: 8583-8588.

44. E. DeIonno, H.-R. Tseng, D. D. Harvey, J. F. Stoddart, J. R. Heath (2006) Infrared Spectroscopic Characterization of [2]Rotaxane Molecular Switch Tunnel Junction Devices. J. Phys. Chem. B 110: 7609-7612.

43. V. Balzani, M. Clemente-León, A. Credi, M. Semeraro, M. Venturi, H.-R. Tseng, S. Wenger, S. Saha, J. F. Stoddart (2006) A Comparison of Shuttling Mechanisms in Two Constitutionally Isomeric Bistable Rotaxane-Based Sunlight-Powered Nanomotors. Aust. J. Chem. 59: 193-206.

42. P. M. Mendes, W. Lu, H.-R. Tseng, S. Shinder, T. Iijima, M. Miyaji, C. M. Knobler, J. F. Stoddart (2006) A Soliton Phenomenon in Langmuir Monolayers of Amphiphilic Bistable Rotaxanes. J. Phys. Chem. B 110: 3845-3848.

41. S. Saha, L. E. Johansson, A. H. Flood, H.-R. Tseng, J. I. Zink, J. F. Stoddart (2005) A Photoactive Molecular Triad as a Nanoscale Power Supply for a Supramolecular Machine. Chem. Eur. J. 11: 6846-6858.

40. K. Nørgaard, B. W. Laursen, S. Nygaard, K. Kjaer, H.-R. Tseng, A.H. Flood, J. F. Stoddart, T. Bjørnholm (2005) Structural Evidence of Mechanical Shuttling in Condensed Monolayers of Rotaxane Molecules. Angew. Chem. Int. Ed. 43: 7035-7039.

39. T. D. Nguyen, H.-R. Tseng, P. C. Celestre, A. H. Flood, Y. Liu, J. F. Stoddard, J. I. Zink (2005) A Reversible Molecular Valve. Proc. Natl. Acad. Sci. USA. 102: 10029-10034.

38. Y. Liu, A. H. Flood, P. A. Bonvallet, S. A. Vignon, B. H. Northrop, H.-R. Tseng, J. O. Jeppesen, T, J. Huang, B. Brough, M. Baller, S. Magonov, S. D. Solares, W. A. Goddard, C.-M. Ho, J. F. Stoddart (2005) Linear Artificial Molecular Muscles. J. Am. Chem. Soc. 127: 9745-9759.

37. S. S. Jang, Y. H. Jang, Y.-H. Kim, W. A., III Goddard, A. H. Flood, B. W. Laursen, H.-R. Tseng, J. F. Stoddart, J. O. Jeppesen, J. W. Choi, D. W. Steuerman, E. DeIonno, J. R. Heath (2005) Structures and Properties of Self-Assembled Monolayers of Bistable [2]Rotaxanes on Au (111) Surfaces from Molecular Dynamics Simulations Validated with Experiment. J. Am. Chem. Soc 127: 1563-1575.

36. A. H. Flood, A. J. Peters, S. A. Vignon, D. W. Steuerman, H.-R. Tseng, S. K. Kang, J. R. Heath, J. F. Stoddart (2004) The Environmental Responsive Electrochemical Switching Mechanism Displayed by Bistable Donor-Acceptor Catenanes and Rotaxanes. Chem. Eur. J. 10: 6558-6564.

35. D. W. Steuerman, H.-R. Tseng, A. J. Peters, A. H. Flood, J. O. Jeppesen, K. A. Nielsen, J. F. Stoddart, J. R. Heath (2004) The Dynamics of Molecular Mechanical Switches within Solid-State Polymer Electrolytes. Angew. Chem. Int. Ed. 43: 6486-6491.

34. T. J. Huang, B. Brough, C.-M. Ho, Y. Liu, A. H. Flood, P. A. Bonvallet, H.-R. Tseng, J. F. Stoddart, M. Baller, S. Magonov (2004) A Nanomechanical Device Based on Linear Molecular Motors. Appl. Phys. Lett. 85: 5391-5393.

33. F. Marchioni, M. Venturi, P. Ceroni, V. Balzani, M. Belohardsky, A. M. Elizarov, H.-R. Tseng, J. F. Stoddart (2004) Complete Charge Pooling is Prevented in Viologen-based Dendrimers by Self-Protection. Chem. Eur. J. 10: 6361-6368.

32. T. Iijima, S. A. Vignon, H.-R. Tseng, T. Jarrosson, J. K. M. Sanders, F. Marchioni, M. Venturi, E. Apostoli, V. Balzani, J. F. Stoddart (2004) Redox-Controllable Donor-Acceptor Neutral [2]Rotaxanes. Chem. Eur. J. 10: 6375-6392.

31. S. Saha, E. Johansson, A. H. Flood, H.-R. TsengJ. I. Zink, J. F. Stoddart (2004) Powering a Supramolecular Machine with a Photoactive Molecular Triad. Small 1: 87-90.

30. T. J. Huang, H.-R. Tseng, L. Sha, W. Lu, A. H. Flood, B. Brough, B. Yu, P. C. Celestre, P. J. Chang, J. F. Stoddart, C.-M. Ho (2004) Mechanical Shuttling of Linear Motor-Molecules in Condensed Phased on Solid substrates. Nano Lett. 4: 2065-2071.

29. S. A. Vignon, T. Jarrosson, T. Iijima, H.-R. Tseng, J. K. M. Sanders, J. F. Stoddart (2004) Switchable Neutral Bistable Rotaxanes. J. Am. Chem. Soc. 126: 9884-9885.

28. C. Lee, C. W. Frank, T. Yamamoto, H.-R. Tseng, A. H. Flood, J. F. Stoddart (2004) Langmuir and Langmuir-Blodgett Films of Amphiphilic Bistable [2]Rotaxanes. Langmuir 20: 5809-5828.

27. R. Hernandez, H.-R. Tseng, J. W. Wong, J. F. Stoddart, J. I. Zink (2004) An Operational Supramolecular Nanovalve. J. Am. Chem. Soc. 126: 3370-3371.

26. S. Kang, S. A. Vignon, H.-R. Tseng, J. F. Stoddart (2004) Molecular Shuttle Based on Tetrathiafulvalene Units and 1,5-Dioxynaphthalene Ring Systems. Chem. Eur. J. 10: 2555-2564.

25. H.-R. Tseng, D. Wu, N. X. Fang, X. Zhang, J. F. Stoddart (2004) The Metastability of an Electrochemical Controlled Nanoscale Machine on Gold Surfaces. ChemPhysChem 5: 111-116.

24. H.-R. Tseng, P. C. Celestre, J. Perkins, J. O. Jeppesen, J. F. Stoddart, P. A. Di Fabio, R. Ballardini, V. Balzani, M. T. Gandolfi, M. Venturi (2004) Redox-Controllable Amphiphilic [2]Rotaxanes. Chem. Eur. J. 10: 155-172.

23. F. Marchioni, M. Venturi, A. Credi, V. Balzani, M. Belohradsky, A. M. Elizarov, H.-R. Tseng, J. F. Stoddart (2004) Polyvalent Scaffold. Counting the Number of Seats Available for Eosin Guest Molecules in Viologen-Based Host Dendrimers. J. Am. Chem. Soc. 126: 568-573.

22. H.-R. Tseng, P. C. Celestre, J. F. Stoddart (2004) An Integrated System-Oriented Approach to Molecular Electronics. Macromolecular Nano-Structure Materials (N. Ueyama, A. Harada, Eds.) Springer-Verlag: Germany : 1-25.

21. S. A. Vignon, J. Wang, H.-R. Tseng, J. F. Stoddart (2004) Helical Chirality in Donor-Acceptor Catenanes. Org. Lett. 6: 1095-1098. 

20. D. Wu, X. Yin, X. Zhang, H.-R. Tseng, J. F. Stoddart (2003) In Situ Infrared Spectroscopic Studies of Molecular Behavior in Nanoelectronic Devices. IEEE-NANO 2: 606-608.

19. T. J. Huang, A. Flood, C.-W. Chu, S. Kang, T.-F. Guo, T. Yamamoto, H.-R. Tseng, B.-D. Yu,  Y. Yang, J. F. Stoddart, C.-M. Ho (2003) In situ Infrared Spectroscopic Studies of Molecular Behavior in Nanoelectronic Devices. IEEE-NANO 2: 698-701.

18. M. R. Bryce, G. Cooke, F. M. A. Dunclairoir, P. John, D. F. Perepichka, N. Polwart, V. M. Rotello, H.-R. Tseng, J. F. Stoddart (2003) Electrochemically Controllable Surfaces with Three-Pole Binding Properties. J. Mater. Chem. 13: 2111-2117.

17. H.-R. Tseng, S. A. Vignon, J. F. Stoddart (2003) Toward Chemically Controlled Nanoscale Molecular Machinery. Angew. Chem. Int. Ed. 42: 1491-1495.

16. H.-R. Tseng, S. A. Vignon, P. C. Celestre, J. F. Stoddart, A. J. P. White, D. J. Williams (2003) Dynamic Chemistry: Keen Selection in the Face of Stereochemical Diversity in Mechanically Bonded Compounds. Chem. Eur. J. 9: 543-556.  

15. T. Yamamoto, H.-R. Tseng, J. F. Stoddart, V. Balzani, A. Credi, F. Marchioni, M. Venturi (2003) Redox-Induced Ring Shuttling and Evidence for Folded Structures in Long and Flexible Two-Station Rotaxanes. Collect. Czech. Chem. Comm. 68: 1488-1514.

14. H.-R. Tseng, S. A. Vignon, J. F. Stoddart (2003) Molecular Muscles Based on Mechanically Interlocked Molecules. Polymer Preprints 44: 377-378.

13. J. F. Stoddart, H.-R. Tseng (2003) Molecular Electronics Based on Mechanically Interlocked Molecules. Polymer Preprints 44: 381-382.

12. M. R. Diehl, D. W. Steuerman, H.-R. Tseng, S. A. Vignon, A. Star, J. F. Stoddart, J. R. Heath (2003) Single-Walled Carbon Nanotube Based Molecular Switch Tunnel Junctions. ChemPhysChem 4: 1335-1339.

11. H. Yu, Y. Luo, K. Beverley, H.-R. Tseng, J. F. Stoddart, J. R. Heath (2003) The Molecule / Electrode Interfaces in Single-Molecule Transistors. Angew. Chem. Int. Ed. 42: 5706-5711.

10. Y. Luo, C. P. Collier, J. O. Jeppesen, K. A. Nielsen, E. DeIonno, G. Ho, J. Perkins, H.-R. Tseng, T. Yamamoto, J. F. Stoddart, J. R. Heath (2002) Two-Dimensional Molecular Electronics Circuits. ChemPhysChem 3: 519-525.  

 9.  R. Ballardini, V. Balzani, M. Clemente-Leon, A. Credi, M. T. Gandolfi, E. Ishow, J. Perkins, J. F. Stoddart, H.-R. Tseng, S. Wenger (2002) Photoinduced Electron Transfer in a Triad That Can Be Assembled / Disassembled by Two Different External Inputs. Toward Molecular-Level Extension Cables. J. Am. Chem. Soc. 124: 12786-12795.

 8.  J. F. Stoddart, H.-R. Tseng (2002) Chemical Synthesis Gets a Fillip from Molecular Recognition and Self-Assembly Processes. Proc. Natl. Acad. Sci. USA 99: 4797-4800.

 7.  H.-R. Tseng, J. F.Stoddart (2002) Molecular Switches and Machines Using Arene Building Blocks. Modern Arene Chemistry (D. Astruc, Ed.) Wiley-VCH: Weinheim : 574-599.

 6.  H.-R. Tseng, C.-F. Lee, L.-M.; Yang, T.-Y. Luh (1999) Umpolung of the Carbon-Sulfur Bonds. Novel Synthesis of Substituted Allenes from Propargylic Ditioacetals. J. Org. Chem. 64: 8582-8587.

 5.  H.-R. Tseng, T.-Y. Luh (1997) Novel Coupling Reaction of Dithioacetals with Organocuprate Reagents. Propargylic Dithioacetal as a Allene-1,3-Zwitterion Synthon. J. Org. Chem. 62: 4568-4569.

 4.  C.-T. Lin, N.-J. Wang, H.-R. Tseng, T.-C. Chou (1997) Synthesis and Transannular Reactions of a Polycylic Compound Containing Three Parallel Face-to-Face Double Bonds. J. Org. Chem. 62: 4857-4861.

 3.  H.-R. Tseng, T.-Y. Luh (1996) Reactions of Geminal Dication Synthons with Geminal Dianionic Species. Cross-Coupling of Benzylic Dithioacetals with Nickela- Bismetallic Reagents. Organometallics 15: 3099-3102.

 2.  H.-R. Tseng, T.-Y. Luh (1996) Propargylic Dithioacetal as an Allene 1,3-Dication Synthon. Nickel-Catalyzed Cross-Coupling Reaction of Propargylic Dithioacetals with Grignard Reagents. J. Org. Chem. 61: 8685-8686.

 1.  H.-R. Tseng, T.-S. Chou (1995) Regioselective Substitution Reactions of Zinc Sulfolenylates. Tetrahedron Letts. 36: 7105-7108.

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Patent Applications

1.   Provisional Application, “An Integrated Microfluidic Blood Sampler for Mice” UCLA Case No.   2005-659-1. (Disclosure date: May 09, 2005)

2.   Provisional Application, “A Simplified Approach for Surface Modification of Polymer-Based Microfluidic Devices” UCLA Case No. 2005-685-1. (Disclosure date: May 31, 2005)

3.   Patent Application “Electrochemically fabricated conducting polymer nanowire sensors” PCT Int. Appl. (2006), WO 2006042276.

4.   Patent Application “Microfluidic devices with chemical reaction circuits” PCT Int. Appl.  (2006), WO 2006071470.

5.   Provisional Application, “Development of High-Affinity PET-Probes for High Performance Molecular Imaging” PCT Int. Appl. (2006), WO 2006778430.

6.   Provisional Application, “Device for High Sensitivity Quantitation of Radioisotope Concentrations in a Microfluidic Platform” UCLA Case No. 2006-388-1. (Disclosure date: January 11, 2006)

7.  Provisional Application, “Microfluidic Platform for Cell Culture and Assay” UCLA Case No. 2007-067. (Disclosure date: August 4, 2006)

8.   Provisional Application, “Microfluidic Cell Culture Array for Drug Screening and Imaging Probe Discovery” UCLA Case No. 2007-562. (Disclosure date: April 13, 2007)

9.   Provisional Application, “Integrated Microfluidics for Parallel Screening of Chemical Reactions” UCLA Case No. 2007-570. (Disclosure date: May 23, 2007)

 

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Last modified: 01.20.2008